54
זכר
רווק
****
מלאה
אין פרטים זמינים
תיכונית, תואר ראשון, תואר שני, דוקטורט
עברית
אנגלית
רוסית
רכב פרטי – רישיון ב'
רכב פרטי
Education
Postdoctoral Fellow (2015 – 2017)
Weizmann Institute of Science, Department of Molecular Genetics, Rehovot, Israel
Research Topic: Regulation of bone cell adhesion and activity of osteoclasts in bone metabolism
for osteoporosis treatment.
Supervisor: Prof. Dr. Ari Elson
Postdoctoral Fellow (2010 – 2014)
Hebrew University of Jerusalem, Department of Bone Biology, Jerusalem, Israel
Research Topics: Cannabinoid regulation of skeletal growth; calcium-phosphate coatings for
titanium implants.
Ph.D. in Science (2004 – 2010)
ETH Zürich, Institute for Biomechanics, Zürich, Switzerland
Thesis: "Differentially Load-Regulated Global Gene Expression in Mouse Trabecular
Osteocytes"
Supervisors: Prof. Dr. Ralph Müller & Prof. Dr. Itai Bab
M.Sc. in Cell Biology (1998 – 2000)
Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
B.Sc. in Life Sciences (1995 – 1997)
Tel-Aviv University, Tel-Aviv, Israe
Professional Experience
Research Scientist and Research Assistant: 2025 - Present
Department of Pediatric Endocrinology, and Yosef Sagol Center for Neuroscience, Sheba
Medical Center, Ramat-Gan, Israel.
Research in advancing the understanding of endocrine disorders. Studying nutritional
hormones and liver organoids, to investigating fatty liver disease and establishing genetic
variants of diabetes.
Typing medical records of the patients into a computerized medical management module
system “REDCup”.
Senior Analyst, QC Department (2019 – 2024)
Omrix Biopharmaceuticals, Inc. (Johnson & Johnson Corp.), Sheba Medical Center, RamatGan, Israel
Planning, execution, and documentation biological, immunological, and biochemical tests
for product quality control in a GMP and Data Integrity environment.
Participation in the validation of analytical methods and ensuring compliance with data
integrity standards.
Supervising and training junior analysts in laboratory procedures and GMP practices.
Senior Scientist (2018 – 2019)
Aposense Ltd., Petach-Tikva, Israel
Performing in-vivo and in-vitro experiments focusing on siRNA-based drug
development.
Designing and execution molecular and cell biology protocols for novel therapeutic
applications.
Research Assistant (2002 – 2004)
ETH Zürich & Hebrew University of Jerusalem
Conducting biomedical engineering and developmental biology research.
Developing methods for cell isolation and gene expression analysis.
Laboratory Technician (1998 – 2002)
Shiloov Company & QBI Enterprises Ltd., Nes-Ziona, Israel
3
Providing technical support in cell biology and histological analysis.
Assistance in protein purification and bioassay development.
Technical Skills
Molecular Biology: DNA and RNA extractions, PCR, qPCR, siRNA, microarray
analysis, gene expression profiling, cloning, NGS library prep, single-cell RNA-seq
Cell Biology: Cell lines culturing, isolation of primary cells, immunohistochemistry,
ELISA, FACS, IVIS spectrum in-vivo imaging, confocal microscopy
Animal Handling: Breeding, genotyping, IP- IV- and SC injections, rodent
microsurgery, knockout mouse models, bone marrow transplantation
Bone Biology Techniques: Micro-CT scanning, histomorphometry, bone microstructure
analysis, micro-PET
Protein Analysis: Western blotting, 2D gel electrophoresis, SDS-PAGE, protein
purification, protein concentration determination by Bradford and Biuret, protein
radioactive assay, co-immunoprecipitation
Analytical Techniques: Chemiluminescent assays (ARCHITECT), atomic emission
spectrometry (flame photometer), UV-Vis spectroscopy, coagulation system for thrombin
potency (activity) determination, density and osmolality products measurement
Selected Publications
1. Wasserman, E., et al. (2019). Phosphorylation of PTPROt at Tyr399 controls osteoclast
activity and bone mass in vivo. Science Signaling.
2. Wasserman, E., et al. (2015). CB1 cannabinoid receptors mediate endochondral skeletal
growth attenuation by Δ9-tetrahydrocannabinol. Annals of the New York Academy of
Science.
3. Wasserman, E., et al. (2013). Differentially load-regulated global gene expression in
mouse trabecular osteocytes. Bone.
4. Wasserman, E., et al. (2010). Mechanical loading of mouse caudal vertebrae increases
trabecular and cortical bone mass. Biomechanics and Modeling in Mechanobiology.
Conference Presentations & Invited Talks
1. "Method for Differential Isolation of RNA from Trabecular Osteoblasts," European
Society of Biomechanics, Lucerne, Switzerland, 2008.
2. "Cannabinoid Regulation of Body Growth," International Cannabinoid Research
Society Symposium, St. Charles, Illinois, USA, 2011.
3. "Cannabinoid Regulation of Skeletal Growth," University of Bonn, Germany, 2012.
4
Advisory & Mentorship Roles
Supervising multiple undergraduate and graduate theses at ETH Zürich Switzerland and
Hebrew University of Jerusalem, Jerusalem, Israel.
Mentoring Ph.D. students in molecular biology and biomechanics research.
Training & Certifications
Molecular Basis for Working with Transgenic Animals (University of Zürich, 2008)
Gene Expression Data Analysis (Functional Genomics Center Zürich, 2007)
Bioinformatics and Micro-Array Data Analysis (Max Planck Institute for Molecular
Genetics, 2005)
Laboratory Animal Science (FELASA-Category B) (University of Zürich, 2003
Experienced scientist and senior analyst with extensive academic and industry experience in
molecular genetics, bone and cellular biology, and drug development. Expertise in molecular and
cell biology techniques, preclinical research, and quality control in GMP and Data Integrity
environments. Proven leadership in supervising and mentoring researchers, with a strong
publication record and collaborative project experience.